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TF106385
 Tree families database The Sanger Institute Beijing Genomics Institute
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Instructions

ADSLMICMU1344.1
ADSLHUMAN1342.7
AdslMOUSE1341
ADSLHORSE1339.6
Adsl_predictedRAT1334.6
PUR8CHICK1334.2
ADSLPONPY1334.2
PUR8BOVIN1332.1
adslXENTR1328.1
ADSLCAVPO1327.9
ADSLCANFA1321.6
ADSLPANTR1321.4
ADSLTETNG1313.7
adslBRARE1312.2
ADSLGASAC1311.5
ADSLOCHPR1283.8
dyak_GLEANR_9687_caf1DROYA1274.3
CG3590-RADROME1273.8
dmoj_GLEANR_13655_caf1DROMO1273.4
dere_GLEANR_1740_caf1DROER1272.9
dsim_GLEANR_4041_caf1DROSI1272.8
dana_GLEANR_19177_caf1DROAN1269.6
dper_GLEANR_5351_caf1DROPE1268.5
dvir_GLEANR_13938_caf1DROVI1267.8
dgri_GLEANR_16062_caf1DROGR1261.7
dwil_GLEANR_14172_caf1DROWI1257.9
ENSCINT00000000763CIOIN1248.1
ENSCSAVT00000013322CIOSA1243.7
XP_312577ANOGA1240.9
Sp-AdslSTRPU1229.8
dsec_GLEANR_16187_caf1DROSE1210.9
ADSLFELCA1208.4
ADSLECHTE1195.9
ADE13YEAST1194.7
ade8SCHPO1171.2
ADSLMONDO1154.7
jgi|Brafl1|117498|estExt_fgeneBRAFL1138
ADSLORNAN1136.6
Smp_038030SCHMA1119.5
ADSLERIEU1040.3
CBG21917CAEBR1014.7
cr01.sctg243.wum.2.1CAERE1011.2
WBGene00011064_F3CAEEL1009.8
ADSLSPETR988.6
ENSCINT00000029700CIOIN982.5
ENSBTAT00000053320BOVIN966.7
ADSLTUPGB949.1
BGIBMGA007119BOMMO905.2
ADSLMYOLU871.2
ADSLRABIT859.7
ADSLMACMU790.9
Bm1_11585ABRUMA698.6
ADSLDASNO671.6
ADSLLOXAF664.4
ADSLOTOGA654
ADSLSORAR374.8
jgi|Helro1|161397|fgenesh4_pg.HELRO22.2
jgi|Capca1|209902|fgenesh1_pg.CAPIT22
jgi|Triad1|61292|fgeneshTA2_pgTRIAD19

Descriptions
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AccessionTF106385
SymbolADSL
Family Nameadenylosuccinate lyase
Family Sizeseed: 16 / full: 55
Old AccessionsTF300501
DescriptionsAdenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy.
Last Modified2006-07-03

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View Automatic Clean Tree
Instructions ATV TreeView

ade8_SCHPO
ADE13_YEAST
Adsl_MOUSE
Adsl_predicted_RAT
ADSL_HUMAN
ADSL_PANTR
ADSL_MACMU
PUR8_BOVIN
ENSBTAT00000053320_BOVIN
ADSL_CANFA
ADSL_MONDO
PUR8_CHICK
adsl_XENTR
adsl_BRARE
ADSL_TETNG
ADSL_F2_GASAC
ENSCINT00000000763_CIOIN
ENSCINT00000029700_CIOIN
ENSCSAVT00000013322_CIOSA
CG3590-RA_DROME
dper_GLEANR_5351_caf1_DROPE
XP_312577_ANOGA
WBGene00011064_F3_CAEEL
CBG21917_CAEBR
cr01.sctg243.wum.2.1_CAERE
Bm1_11585A_BRUMA
Smp_038030_SCHMA


View Curated Seed Tree
Instructions ATV TreeView

ade8_SCHPO
ADE13_YEAST
ADSL_HUMAN
Adsl_MOUSE
ENSMODT00000016479_MONDO
PUR8_CHICK
Q6GLC2_XENTR
adsl_BRARE
NEWSINFRUT00000177480_FUGRU
ENSCINT00000000763_CIOIN
ENSCINT00000029700_CIOIN
NP_650586_DROME
GA17542-PA_DROPS
Sm00.scaff00108.0120_SCHMA
CBG21917_CAEBR
PUR8_CAEEL

View MultiAlignment
Instructions

AGAP002378
chromosome2R: 20816215-20817738
Taxon: Anopheles gambiae [7165]
Bm1_11585A
Bmal_supercontig13736: 44112-48614
Taxon: Brugia malayi [6279]
CBG21917
orthologous to R06C7.5 by best mutual match (eval=0)
cb25.fpc4292: 99209-100904
Taxon: Caenorhabditis briggsae [6238]
cr01.sctg243.wum.2
Contig243.eannot.036.final.final
Contig243: 10055-16426
Taxon: Caenorhabditis remanei [31234]
dana_GLEANR_19177_caf1
scaffold_13340: 7056341-7057786
Taxon: Drosophila ananassae [7217]
dere_GLEANR_1740_caf1
scaffold_4770: 8783818-8785263
Taxon: Drosophila erecta [7220]
dgri_GLEANR_16062_caf1
scaffold_15110: 9439710-9441155
Taxon: Drosophila grimshawi [7222]
dmoj_GLEANR_13655_caf1
scaffold_6680: 18942188-18943633
Taxon: Drosophila mojavensis [7230]
dper_GLEANR_5351_caf1
scaffold_0: 11713394-11714839
Taxon: Drosophila persimilis [7234]
dsec_GLEANR_16187_caf1
scaffold_12: 1309388-1310833
Taxon: Drosophila sechellia [7238]
dsim_GLEANR_4041_caf1
3R: 8626514-8627959
Taxon: Drosophila simulans [7240]
dvir_GLEANR_13938_caf1
scaffold_13049: 24313874-24315319
Taxon: Drosophila virilis [7244]
dwil_GLEANR_14172_caf1
scf2_1100000004943: 4702561-4704092
Taxon: Drosophila willistoni [7260]
dyak_GLEANR_9687_caf1
3R: 11537297-11538742
Taxon: Drosophila yakuba [7245]
ENSBTAG00000000077
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:A3KN12]
chromosome5: 118826780-118843372
Taxon: Bos taurus [9913]
ENSBTAG00000008477
chromosome29: 49262694-49264695
Taxon: Bos taurus [9913]
ENSCAFG00000001206
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome10: 27879097-27897254
Taxon: Canis familiaris [9615]
ENSCING00000000420
scaffoldscaffold_95: 363217-365942
Taxon: Ciona intestinalis [7719]
ENSCING00000000418
scaffoldscaffold_334: 36102-37520
Taxon: Ciona intestinalis [7719]
ENSCPOG00000005715
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1191: 346686-364296
Taxon: Cavia porcellus [10141]
ENSCSAVG00000007729
reftigreftig_41: 1795562-1797020
Taxon: Ciona savignyi [51511]
ENSDARG00000017049
adenylosuccinate lyase [Source:RefSeq_peptide;Acc:NP_956193]
chromosome3: 20021924-20033068
Taxon: Danio rerio [7955]
ENSDNOG00000019330
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1195: 6546-22900
Taxon: Dasypus novemcinctus [9361]
ENSECAG00000021492
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome28: 37011648-37026920
Taxon: Equus caballus [9796]
ENSEEUG00000014245
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1360: 3616-32898
Taxon: Erinaceus europaeus [9365]
ENSETEG00000006576
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1320: 91360-111639
Taxon: Echinops telfairi [9371]
ENSFCAG00000004798
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_735: 316455-347460
Taxon: Felis catus [9685]
ENSGACG00000008181
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
groupgroupXI: 5089004-5093463
Taxon: Gasterosteus aculeatus [69293]
ENSGALG00000012034
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P21265]
chromosome1: 51977410-51993086
Taxon: Gallus gallus [9031]
ENSLAFG00000014483
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1157: 94564-115370
Taxon: Loxodonta africana [9785]
ENSMICG00000014085
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_727: 185317-203159
Taxon: Microcebus murinus [30608]
ENSMLUG00000005441
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
scaffoldscaffold_143480: 142607-153019
Taxon: Myotis lucifugus [59463]
ENSMMUG00000005341
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome10: 84281180-84295572
Taxon: Macaca mulatta [9544]
ENSMODG00000012930
NULL
chromosome8: 9626550-9633091
Taxon: Monodelphis domestica [13616]
ENSMUSG00000022407
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P54822]
chromosome15: 80778977-80799178
Taxon: Mus musculus [10090]
ENSOANG00000014669
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
ultracontigUltra454: 515173-525706
Taxon: Ornithorhynchus anatinus [9258]
ENSOCUG00000016161
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1034: 295725-308514
Taxon: Oryctolagus cuniculus [9986]
ENSOGAG00000015435
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_812: 6061-23990
Taxon: Otolemur garnettii [30611]
ENSOPRG00000012084
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_743: 461924-479955
Taxon: Ochotona princeps [9978]
ENSPPYG00000011850
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome22: 35582544-35602888
Taxon: Pongo pygmaeus [9600]
ENSPTRG00000014407
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome22: 39346867-39368680
Taxon: Pan troglodytes [9598]
ENSRNOG00000018655
chromosome7: 119223622-119247695
Taxon: Rattus norvegicus [10116]
ENSSARG00000004537
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_1074: 16777-24916
Taxon: Sorex araneus [42254]
ENSSTOG00000000979
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_882: 4652-20924
Taxon: Spermophilus tridecemlineatus [43179]
ENSG00000100357
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosome22: 39072508-39092472
Taxon: Homo sapiens [9606]
ENSTBEG00000017523
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
genescaffoldGeneScaffold_821: 173104-200327
Taxon: Tupaia belangeri [37347]
ENSTNIG00000011497
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:P30566]
chromosomeUn_random: 6460094-6463841
Taxon: Tetraodon nigroviridis [99883]
ENSXETG00000006328
Adenylosuccinate lyase. [Source:Uniprot/SPTREMBL;Acc:Q6GLC2]
scaffoldscaffold_88: 108041-116580
Taxon: Xenopus tropicalis [8364]
FBgn0038467
chromosome3R: 12845270-12846716
Taxon: Drosophila melanogaster [7227]
R06C7.5
The R06C7.5 gene encodes an ortholog of the human gene ADSL, which when mutated leads to adenylosuccinate lyase deficiency (OMIM:103050). [Source: WormBase]
chromosomeI: 7246997-7248674
Taxon: Caenorhabditis elegans [6239]
Smp_038030
adenylosuccinate lyase, putative
Smp_scaff000091: 342833-358822
Taxon: Schistosoma mansoni [6183]
SPBC14F5.09c
adenylosuccinate lyase Ade8
chromosome2: 4173998-4175447
Taxon: Schizosaccharomyces pombe [4896]
YLR359W
Adenylosuccinate lyase (EC 4.3.2.2) (Adenylosuccinase) (ASL) (ASASE). [Source:Uniprot/SWISSPROT;Acc:Q05911]
chromosomeXII: 844280-845729
Taxon: Saccharomyces cerevisiae [4932]
Last Modified Thu Aug 2 03:14:18 2007 treefam@sanger.ac.uk